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RAD51 supports spontaneous non-homologous recombination in mammalian cells, but not the corresponding process induced by topoisomerase inhibitors

The RAD51 protein has been shown to participate in homologous recombination by promoting ATP-dependent homologous pairing and strand transfer reactions. In the present study, we have investigated the possible involvement of RAD51 in non-homologous recombination. We demonstrate that overexpression of...

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Main Authors: Arnaudeau, Catherine, Rozier, Lorène, Cazaux, Christophe, Defais, Martine, Jenssen, Dag, Helleday, Thomas
格式: Artigo
語言:Inglês
出版: Oxford University Press 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC30407/
https://ncbi.nlm.nih.gov/pubmed/11160887
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