Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes
Abstract Homologous recombination (HR) is an essential double-stranded DNA break repair pathway. In HR, Rad52 facilitates the formation of Rad51 nucleoprotein filaments on RPA-coated ssDNA. Here, we decipher how Rad52 functions using single-particle cryo-electron microscopy and biophysical approache...
Bewaard in:
| Hoofdauteurs: | , , , , , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Portfolio
2023-10-01
|
| Reeks: | Nature Communications |
| Online toegang: | https://doi.org/10.1038/s41467-023-41993-1 |
| Tags: |
Geen labels, Wees de eerste die dit record labelt!
|