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Human DNA Polymerase η Is Required for Common Fragile Site Stability during Unperturbed DNA Replication

Human DNA polymerase η (Pol η) modulates susceptibility to skin cancer by promoting translesion DNA synthesis (TLS) past sunlight-induced cyclobutane pyrimidine dimers. Despite its well-established role in TLS synthesis, the role of Pol η in maintaining genome stability in the absence of external DN...

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Detaylı Bibliyografya
Asıl Yazarlar: Rey, Laurie, Sidorova, Julia M., Puget, Nadine, Boudsocq, François, Biard, Denis S. F., Monnat, Raymond J., Cazaux, Christophe, Hoffmann, Jean-Sébastien
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698728/
https://ncbi.nlm.nih.gov/pubmed/19380493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00115-09
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