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Human DNA Polymerase η Is Required for Common Fragile Site Stability during Unperturbed DNA Replication
Human DNA polymerase η (Pol η) modulates susceptibility to skin cancer by promoting translesion DNA synthesis (TLS) past sunlight-induced cyclobutane pyrimidine dimers. Despite its well-established role in TLS synthesis, the role of Pol η in maintaining genome stability in the absence of external DN...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698728/ https://ncbi.nlm.nih.gov/pubmed/19380493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00115-09 |
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