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Targeting ATR/CHK1 pathway in acute myeloid leukemia to overcome chemoresistance
Resistance of acute myeloid leukemia to current therapies leads to frequent relapses. Identification of molecular mechanisms involved in chemoresistance constitutes a key challenge to define new therapeutic concepts. Here, we show that the ATR/CHK1 pathway, essential in maintaining genomic stability...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5644474/ https://ncbi.nlm.nih.gov/pubmed/29057300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1289293 |
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