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Disrupting the endothelin and Wnt relationship to overcome chemoresistance

Knowledge of the mechanisms underlying chemoresistance is important in the development of novel targeted treatments for ovarian cancer. We recently reported that targeting endothelin A receptor/β-arrestin-1, a binding partner of Wnt/β-catenin, is sufficient to sensitize ovarian cancer to chemotherap...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Rosanò, Laura, Bagnato, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905315/
https://ncbi.nlm.nih.gov/pubmed/27308478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.995025
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