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Disrupting the endothelin and Wnt relationship to overcome chemoresistance

Knowledge of the mechanisms underlying chemoresistance is important in the development of novel targeted treatments for ovarian cancer. We recently reported that targeting endothelin A receptor/β-arrestin-1, a binding partner of Wnt/β-catenin, is sufficient to sensitize ovarian cancer to chemotherap...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Oncol
Prif Awduron: Rosanò, Laura, Bagnato, Anna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905315/
https://ncbi.nlm.nih.gov/pubmed/27308478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.995025
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