Targeting ATR/CHK1 pathway in acute myeloid leukemia to overcome chemoresistance

Resistance of acute myeloid leukemia to current therapies leads to frequent relapses. Identification of molecular mechanisms involved in chemoresistance constitutes a key challenge to define new therapeutic concepts. Here, we show that the ATR/CHK1 pathway, essential in maintaining genomic stability...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Oncol
Prif Awduron: David, Laure, Manenti, Stéphane, Récher, Christian, Hoffmann, Jean-Sébastien, Didier, Christine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2017
Pynciau:
Author's View
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644474/
https://ncbi.nlm.nih.gov/pubmed/29057300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1289293
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