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Fork-like DNA templates support bypass replication of lesions that block DNA synthesis on single-stranded templates

DNA replication is an asymmetric process involving concurrent DNA synthesis on leading and lagging strands. Leading strand synthesis proceeds concomitantly with fork opening, whereas synthesis of the lagging strand essentially takes place on a single-stranded template. The effect of this duality on...

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Autors principals: Hoffmann, Jean-Sébastien, Pillaire, Marie-Jeanne, Lesca, Claire, Burnouf, Dominique, Fuchs, Robert P. P., Defais, Martine, Villani, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19419/
https://ncbi.nlm.nih.gov/pubmed/8943009
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