Fork-like DNA templates support bypass replication of lesions that block DNA synthesis on single-stranded templates

DNA replication is an asymmetric process involving concurrent DNA synthesis on leading and lagging strands. Leading strand synthesis proceeds concomitantly with fork opening, whereas synthesis of the lagging strand essentially takes place on a single-stranded template. The effect of this duality on...

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Hlavní autoři: Hoffmann, Jean-Sébastien, Pillaire, Marie-Jeanne, Lesca, Claire, Burnouf, Dominique, Fuchs, Robert P. P., Defais, Martine, Villani, Giuseppe
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences of the USA 1996
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC19419/
https://ncbi.nlm.nih.gov/pubmed/8943009
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