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Fork-like DNA templates support bypass replication of lesions that block DNA synthesis on single-stranded templates

DNA replication is an asymmetric process involving concurrent DNA synthesis on leading and lagging strands. Leading strand synthesis proceeds concomitantly with fork opening, whereas synthesis of the lagging strand essentially takes place on a single-stranded template. The effect of this duality on...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Hoffmann, Jean-Sébastien, Pillaire, Marie-Jeanne, Lesca, Claire, Burnouf, Dominique, Fuchs, Robert P. P., Defais, Martine, Villani, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19419/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943009/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.13766
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