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DNA replication stress triggers rapid DNA replication fork breakage by Artemis and XPF
DNA replication stress (DRS) leads to the accumulation of stalled DNA replication forks leaving a fraction of genomic loci incompletely replicated, a source of chromosomal rearrangements during their partition in mitosis. MUS81 is known to limit the occurrence of chromosomal instability by processin...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6085069/ https://ncbi.nlm.nih.gov/pubmed/30059501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007541 |
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