Artemis‐dependent DNA double‐strand break formation at stalled replication forks

Stalled replication forks undergo DNA double‐strand breaks (DSBs) under certain conditions. However, the precise mechanism underlying DSB induction and the cellular response to persistent replication fork stalling are not fully understood. Here we show that, in response to hydroxyurea exposure, DSBs...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Unno, Junya, Takagi, Masatoshi, Piao, Jinhua, Sugimoto, Masataka, Honda, Fumiko, Maeda, Daisuke, Masutani, Mitsuko, Kiyono, Tohru, Watanabe, Fumiaki, Morio, Tomohiro, Teraoka, Hirobumi, Mizutani, Shuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657233/
https://ncbi.nlm.nih.gov/pubmed/23465063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12144
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