Artemis‐dependent DNA double‐strand break formation at stalled replication forks

Stalled replication forks undergo DNA double‐strand breaks (DSBs) under certain conditions. However, the precise mechanism underlying DSB induction and the cellular response to persistent replication fork stalling are not fully understood. Here we show that, in response to hydroxyurea exposure, DSBs...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Unno, Junya, Takagi, Masatoshi, Piao, Jinhua, Sugimoto, Masataka, Honda, Fumiko, Maeda, Daisuke, Masutani, Mitsuko, Kiyono, Tohru, Watanabe, Fumiaki, Morio, Tomohiro, Teraoka, Hirobumi, Mizutani, Shuki
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2013
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657233/
https://ncbi.nlm.nih.gov/pubmed/23465063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12144
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