Artemis‐dependent DNA double‐strand break formation at stalled replication forks

Stalled replication forks undergo DNA double‐strand breaks (DSBs) under certain conditions. However, the precise mechanism underlying DSB induction and the cellular response to persistent replication fork stalling are not fully understood. Here we show that, in response to hydroxyurea exposure, DSBs...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Unno, Junya, Takagi, Masatoshi, Piao, Jinhua, Sugimoto, Masataka, Honda, Fumiko, Maeda, Daisuke, Masutani, Mitsuko, Kiyono, Tohru, Watanabe, Fumiaki, Morio, Tomohiro, Teraoka, Hirobumi, Mizutani, Shuki
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2013
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657233/
https://ncbi.nlm.nih.gov/pubmed/23465063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12144
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