DNA Lesions Induced by Replication Stress Trigger Mitotic Aberration and Tetraploidy Development

During tumorigenesis, cells acquire immortality in association with the development of genomic instability. However, it is still elusive how genomic instability spontaneously generates during the process of tumorigenesis. Here, we show that precancerous DNA lesions induced by oncogene acceleration,...

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Hlavní autoři: Ichijima, Yosuke, Yoshioka, Ken-ichi, Yoshioka, Yoshiko, Shinohe, Keitaro, Fujimori, Hiroaki, Unno, Junya, Takagi, Masatoshi, Goto, Hidemasa, Inagaki, Masaki, Mizutani, Shuki, Teraoka, Hirobumi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809090/
https://ncbi.nlm.nih.gov/pubmed/20098673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008821
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