DNA Lesions Induced by Replication Stress Trigger Mitotic Aberration and Tetraploidy Development

During tumorigenesis, cells acquire immortality in association with the development of genomic instability. However, it is still elusive how genomic instability spontaneously generates during the process of tumorigenesis. Here, we show that precancerous DNA lesions induced by oncogene acceleration,...

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Detaylı Bibliyografya
Asıl Yazarlar: Ichijima, Yosuke, Yoshioka, Ken-ichi, Yoshioka, Yoshiko, Shinohe, Keitaro, Fujimori, Hiroaki, Unno, Junya, Takagi, Masatoshi, Goto, Hidemasa, Inagaki, Masaki, Mizutani, Shuki, Teraoka, Hirobumi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809090/
https://ncbi.nlm.nih.gov/pubmed/20098673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008821
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