14-3-3γ mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage

14-3-3 proteins control various cellular processes, including cell cycle progression and DNA damage checkpoint. At the DNA damage checkpoint, some subtypes of 14-3-3 (β and ζ isoforms in mammalian cells and Rad24 in fission yeast) bind to Ser345-phosphorylated Chk1 and promote its nuclear retention....

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Kasahara, Kousuke, Goto, Hidemasa, Enomoto, Masato, Tomono, Yasuko, Kiyono, Tohru, Inagaki, Masaki
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2010
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924644/
https://ncbi.nlm.nih.gov/pubmed/20639859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.157
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk