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14-3-3γ mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage
14-3-3 proteins control various cellular processes, including cell cycle progression and DNA damage checkpoint. At the DNA damage checkpoint, some subtypes of 14-3-3 (β and ζ isoforms in mammalian cells and Rad24 in fission yeast) bind to Ser345-phosphorylated Chk1 and promote its nuclear retention....
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924644/ https://ncbi.nlm.nih.gov/pubmed/20639859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.157 |
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