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P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation

The ataxia telangiectasia mutated- and rad3-related kinase (ATR)/Chk1 pathway is a sentinel of cell cycle progression. On the other hand, the Ras/mitogen-activated protein kinase/90-kDa ribosomal S6 kinase (p90 RSK) pathway is a central node in cell signaling downstream of growth factors. These path...

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Bibliografiske detaljer
Main Authors: Li, Ping, Goto, Hidemasa, Kasahara, Kousuke, Matsuyama, Makoto, Wang, Zhonghua, Yatabe, Yasushi, Kiyono, Tohru, Inagaki, Masaki
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327324/
https://ncbi.nlm.nih.gov/pubmed/22357623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-10-0883
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