Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells

The primary cilium is an antenna-like organelle that modulates differentiation, sensory functions, and signal transduction. After cilia are disassembled at the G0/G1 transition, formation of cilia is strictly inhibited in proliferating cells. However, the mechanisms of this inhibition are unknown. I...

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Main Authors: Inoko, Akihito, Matsuyama, Makoto, Goto, Hidemasa, Ohmuro-Matsuyama, Yuki, Hayashi, Yuko, Enomoto, Masato, Ibi, Miho, Urano, Takeshi, Yonemura, Shigenobu, Kiyono, Tohru, Izawa, Ichiro, Inagaki, Masaki
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2012
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341160/
https://ncbi.nlm.nih.gov/pubmed/22529102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201106101
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