Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein–Aurora A pathway

Primary cilia protrude from the surface of quiescent cells and disassemble at cell cycle reentry. We previously showed that ciliary reassembly is suppressed by trichoplein-mediated Aurora A activation pathway in growing cells. Here, we report that Ndel1, a well-known modulator of dynein activity, lo...

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Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Inaba, Hironori, Goto, Hidemasa, Kasahara, Kousuke, Kumamoto, Kanako, Yonemura, Shigenobu, Inoko, Akihito, Yamano, Shotaro, Wanibuchi, Hideki, He, Dongwei, Goshima, Naoki, Kiyono, Tohru, Hirotsune, Shinji, Inagaki, Masaki
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2016
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754717/
https://ncbi.nlm.nih.gov/pubmed/26880200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201507046
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