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Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells
The primary cilium is an antenna-like organelle that modulates differentiation, sensory functions, and signal transduction. After cilia are disassembled at the G0/G1 transition, formation of cilia is strictly inhibited in proliferating cells. However, the mechanisms of this inhibition are unknown. I...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341160/ https://ncbi.nlm.nih.gov/pubmed/22529102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201106101 |
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