Artemis‐dependent DNA double‐strand break formation at stalled replication forks

Stalled replication forks undergo DNA double‐strand breaks (DSBs) under certain conditions. However, the precise mechanism underlying DSB induction and the cellular response to persistent replication fork stalling are not fully understood. Here we show that, in response to hydroxyurea exposure, DSBs...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Unno, Junya, Takagi, Masatoshi, Piao, Jinhua, Sugimoto, Masataka, Honda, Fumiko, Maeda, Daisuke, Masutani, Mitsuko, Kiyono, Tohru, Watanabe, Fumiaki, Morio, Tomohiro, Teraoka, Hirobumi, Mizutani, Shuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2013
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657233/
https://ncbi.nlm.nih.gov/pubmed/23465063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12144
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