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Replication fork inhibition in seqA mutants of E. coli triggers replication fork breakage

SeqA protein negatively regulates replication initiation in E. coli and is also proposed to organize maturation and segregation of the newly-replicated DNA. The seqA mutants suffer from chromosomal fragmentation; since this fragmentation is attributed to defective segregation or nucleoid compaction,...

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Detaylı Bibliyografya
Asıl Yazarlar: Rotman, Ella, Khan, Sharik, Kouzminova, Elena, Kuzminov, Andrei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078979/
https://ncbi.nlm.nih.gov/pubmed/24806348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12638
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