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Replication Forks Stalled at Ultraviolet Lesions Are Rescued via RecA and RuvABC Protein-catalyzed Disintegration in Escherichia coli

Ultraviolet (UV) irradiation is not known to induce chromosomal fragmentation in sublethal doses, and yet UV irradiation causes genetic instability and cancer, suggesting that chromosomes are fragmented. Here we show that UV irradiation induces fragmentation in sublethal doses, but the broken chromo...

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Bibliografische gegevens
Hoofdauteurs: Khan, Sharik R., Kuzminov, Andrei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307332/
https://ncbi.nlm.nih.gov/pubmed/22194615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322990
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