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Replication Forks Stalled at Ultraviolet Lesions Are Rescued via RecA and RuvABC Protein-catalyzed Disintegration in Escherichia coli

Ultraviolet (UV) irradiation is not known to induce chromosomal fragmentation in sublethal doses, and yet UV irradiation causes genetic instability and cancer, suggesting that chromosomes are fragmented. Here we show that UV irradiation induces fragmentation in sublethal doses, but the broken chromo...

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書目詳細資料
Main Authors: Khan, Sharik R., Kuzminov, Andrei
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307332/
https://ncbi.nlm.nih.gov/pubmed/22194615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322990
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