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Replication Forks Stalled at Ultraviolet Lesions Are Rescued via RecA and RuvABC Protein-catalyzed Disintegration in Escherichia coli

Ultraviolet (UV) irradiation is not known to induce chromosomal fragmentation in sublethal doses, and yet UV irradiation causes genetic instability and cancer, suggesting that chromosomes are fragmented. Here we show that UV irradiation induces fragmentation in sublethal doses, but the broken chromo...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Khan, Sharik R., Kuzminov, Andrei
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307332/
https://ncbi.nlm.nih.gov/pubmed/22194615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322990
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