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Replication Forks Stalled at Ultraviolet Lesions Are Rescued via RecA and RuvABC Protein-catalyzed Disintegration in Escherichia coli

Ultraviolet (UV) irradiation is not known to induce chromosomal fragmentation in sublethal doses, and yet UV irradiation causes genetic instability and cancer, suggesting that chromosomes are fragmented. Here we show that UV irradiation induces fragmentation in sublethal doses, but the broken chromo...

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Sonraí Bibleagrafaíochta
Main Authors: Khan, Sharik R., Kuzminov, Andrei
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307332/
https://ncbi.nlm.nih.gov/pubmed/22194615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322990
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