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Impairment of lagging strand synthesis triggers the formation of a RuvABC substrate at replication forks
The holD gene codes for the ψ subunit of the Escherichia coli DNA polymerase III holoenzyme, a component of the γ complex clamp loader. A holD mutant was isolated for the first time in a screen for mutations that increase the frequency of tandem repeat deletions. In contrast to tandem repeat deletio...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133471/ https://ncbi.nlm.nih.gov/pubmed/11157768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.3.619 |
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