Impairment of lagging strand synthesis triggers the formation of a RuvABC substrate at replication forks
The holD gene codes for the ψ subunit of the Escherichia coli DNA polymerase III holoenzyme, a component of the γ complex clamp loader. A holD mutant was isolated for the first time in a screen for mutations that increase the frequency of tandem repeat deletions. In contrast to tandem repeat deletio...
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| Published in: | EMBO J |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133471/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11157768/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.3.619 |
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