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Impairment of lagging strand synthesis triggers the formation of a RuvABC substrate at replication forks

The holD gene codes for the ψ subunit of the Escherichia coli DNA polymerase III holoenzyme, a component of the γ complex clamp loader. A holD mutant was isolated for the first time in a screen for mutations that increase the frequency of tandem repeat deletions. In contrast to tandem repeat deletio...

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Detalhes bibliográficos
Main Authors: Flores, Maria-Jose, Bierne, Hélène, Ehrlich, S.Dusko, Michel, Bénédicte
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133471/
https://ncbi.nlm.nih.gov/pubmed/11157768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.3.619
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