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Replication slippage involves DNA polymerase pausing and dissociation

Genome rearrangements can take place by a process known as replication slippage or copy-choice recombination. The slippage occurs between repeated sequences in both prokaryotes and eukaryotes, and is invoked to explain microsatellite instability, which is related to several human diseases. We analys...

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Detalhes bibliográficos
Main Authors: Viguera, Enrique, Canceill, Danielle, Ehrlich, S.Dusko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125466/
https://ncbi.nlm.nih.gov/pubmed/11350948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.10.2587
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