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SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms

The SeqA protein binds hemi-methylated GATC sites and forms structures that sequester newly replicated origins and trail the replication forks. Cells that lack SeqA display signs of replication fork disintegration. The broken forks could arise because of over-initiation (the launching of too many fo...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Pedersen, Ida Benedikte, Helgesen, Emily, Flåtten, Ingvild, Fossum-Raunehaug, Solveig, Skarstad, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499823/
https://ncbi.nlm.nih.gov/pubmed/28407100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx263
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