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SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms

The SeqA protein binds hemi-methylated GATC sites and forms structures that sequester newly replicated origins and trail the replication forks. Cells that lack SeqA display signs of replication fork disintegration. The broken forks could arise because of over-initiation (the launching of too many fo...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Pedersen, Ida Benedikte, Helgesen, Emily, Flåtten, Ingvild, Fossum-Raunehaug, Solveig, Skarstad, Kirsten
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499823/
https://ncbi.nlm.nih.gov/pubmed/28407100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx263
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