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SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms
The SeqA protein binds hemi-methylated GATC sites and forms structures that sequester newly replicated origins and trail the replication forks. Cells that lack SeqA display signs of replication fork disintegration. The broken forks could arise because of over-initiation (the launching of too many fo...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499823/ https://ncbi.nlm.nih.gov/pubmed/28407100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx263 |
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