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Replication fork movement and methylation govern SeqA binding to the Escherichia coli chromosome

In Escherichia coli, the SeqA protein binds specifically to GATC sequences which are methylated on the A of the old strand but not on the new strand. Such hemimethylated DNA is produced by progression of the replication forks and lasts until Dam methyltransferase methylates the new strand. It is the...

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Detalhes bibliográficos
Main Authors: Waldminghaus, Torsten, Weigel, Christoph, Skarstad, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384311/
https://ncbi.nlm.nih.gov/pubmed/22373925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks187
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