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Replication fork movement and methylation govern SeqA binding to the Escherichia coli chromosome

In Escherichia coli, the SeqA protein binds specifically to GATC sequences which are methylated on the A of the old strand but not on the new strand. Such hemimethylated DNA is produced by progression of the replication forks and lasts until Dam methyltransferase methylates the new strand. It is the...

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Hlavní autoři: Waldminghaus, Torsten, Weigel, Christoph, Skarstad, Kirsten
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384311/
https://ncbi.nlm.nih.gov/pubmed/22373925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks187
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