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Replication fork movement and methylation govern SeqA binding to the Escherichia coli chromosome
In Escherichia coli, the SeqA protein binds specifically to GATC sequences which are methylated on the A of the old strand but not on the new strand. Such hemimethylated DNA is produced by progression of the replication forks and lasts until Dam methyltransferase methylates the new strand. It is the...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384311/ https://ncbi.nlm.nih.gov/pubmed/22373925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks187 |
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