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Topoisomerase IV tracks behind the replication fork and the SeqA complex during DNA replication in Escherichia coli

Topoisomerase IV (TopoIV) is a vital bacterial enzyme which disentangles newly replicated DNA and enables segregation of daughter chromosomes. In bacteria, DNA replication and segregation are concurrent processes. This means that TopoIV must continually remove inter-DNA linkages during replication....

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Helgesen, Emily, Sætre, Frank, Skarstad, Kirsten
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803763/
https://ncbi.nlm.nih.gov/pubmed/33436807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80043-4
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