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RecA-dependent mutants in Escherichia coli reveal strategies to avoid chromosomal fragmentation

RecA- and RecBC-catalyzed repair in eubacteria assembles chromosomes fragmented by double-strand breaks. We propose that recA mutants, being unable to repair fragmented chromosomes, depend on various strategies designed to avoid chromosomal fragmentation. To identify chromosomal fragmentation-avoida...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Kouzminova, Elena A., Rotman, Ella, Macomber, Lee, Zhang, Jian, Kuzminov, Andrei
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC528955/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15531636/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0405943101
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