Llwytho...
RNase HII saves rnhA mutant Escherichia coli from R-loop-associated chromosomal fragmentation
The rnhAB mutant E. coli, deficient in two RNase H enzymes that remove both R-loops and incorporated ribonucleotides (rNs) from DNA, grow slowly, suggesting accumulation of rN-containing DNA lesions (R-lesions). We report that the rnhAB mutants have reduced viability, form filaments with abnormal nu...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Mol Biol |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5610948/ https://ncbi.nlm.nih.gov/pubmed/28821455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.08.004 |
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