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Substrate-selective repair and restart of replication forks by DNA translocases

Stalled replication forks are sources of genetic instability. Multiple fork remodeling enzymes are recruited to stalled forks, but how they work to promote fork restart is poorly understood. By combining ensemble biochemical assays and single molecule studies with magnetic tweezers, we show that SMA...

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Autors principals: Bétous, Rémy, Couch, Frank. B., Mason, Aaron C., Eichman, Brandt F., Manosas, Maria, Cortez, David
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700663/
https://ncbi.nlm.nih.gov/pubmed/23746452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.05.002
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