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Direct observation of stalled fork restart via fork regression in the T4 replication system

The restart of a stalled replication fork is a major challenge for DNA replication. Depending upon the nature of the damage, different repair processes might be triggered; one is template switching that is bypass of a leading strand lesion via fork regression. Using magnetic tweezers to study the T4...

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Main Authors: Manosas, Maria, Perumal, Senthil K., Croquette, Vincent, Benkovic, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858903/
https://ncbi.nlm.nih.gov/pubmed/23197534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1225437
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