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Response of the bacteriophage T4 replisome to non-coding lesions and regression of a stalled replication fork

DNA is constantly damaged by endogenous and exogenous agents. The resulting DNA lesions have the potential to halt the progression of the replisome, possibly leading to replication fork collapse. Here, we examine the effect of a non-coding DNA lesion in either the leading or lagging strand template...

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Detalhes bibliográficos
Main Authors: Nelson, Scott W., Benkovic, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943651/
https://ncbi.nlm.nih.gov/pubmed/20600127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.06.027
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