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Understanding DNA replication by the bacteriophage T4 replisome

The T4 replisome has provided a unique opportunity to investigate the intricacies of DNA replication. We present a comprehensive review of this system focusing on the following: its 8-protein composition, their individual and synergistic activities, and assembly in vitro and in vivo into a replisome...

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Pubblicato in:J Biol Chem
Autori principali: Benkovic, Stephen J., Spiering, Michelle M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682956/
https://ncbi.nlm.nih.gov/pubmed/28972188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.811208
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