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Coupling DNA unwinding activity with primer synthesis in the bacteriophage T4 primosome
The unwinding and priming activities of the bacteriophage T4 primosome, which consists of a hexameric helicase (gp41) translocating 5′ to 3′ and an oligomeric primase (gp61) synthesizing primers 5′ to 3′, has been investigated on DNA hairpins manipulated by a magnetic trap. We find that the T4 primo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784132/ https://ncbi.nlm.nih.gov/pubmed/19838204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.236 |
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