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Real-time observation of bacteriophage T4 gp41 helicase reveals an unwinding mechanism

Helicases are enzymes that couple ATP hydrolysis to the unwinding of double-stranded (ds) nucleic acids. The bacteriophage T4 helicase (gp41) is a hexameric helicase that promotes DNA replication within a highly coordinated protein complex termed the replisome. Despite recent progress, the gp41 unwi...

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Bibliografiske detaljer
Main Authors: Lionnet, Timothée, Spiering, Michelle M., Benkovic, Stephen J., Bensimon, David, Croquette, Vincent
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148377/
https://ncbi.nlm.nih.gov/pubmed/18077411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709793104
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