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Architecture of the bacteriophage T4 primosome: Electron microscopy studies of helicase (gp41) and primase (gp61)

Replication of DNA requires helicase and primase activities as part of a primosome assembly. In bacteriophage T4, helicase and primase are separate polypeptides for which little structural information is available and whose mechanism of association within the primosome is not yet understood. Three-d...

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Autors principals: Norcum, Mona T., Warrington, J. Anthony, Spiering, Michelle M., Ishmael, Faoud T., Trakselis, Michael A., Benkovic, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC553339/
https://ncbi.nlm.nih.gov/pubmed/15738414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500713102
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