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Architecture of the bacteriophage T4 primosome: Electron microscopy studies of helicase (gp41) and primase (gp61)

Replication of DNA requires helicase and primase activities as part of a primosome assembly. In bacteriophage T4, helicase and primase are separate polypeptides for which little structural information is available and whose mechanism of association within the primosome is not yet understood. Three-d...

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Autori principali: Norcum, Mona T., Warrington, J. Anthony, Spiering, Michelle M., Ishmael, Faoud T., Trakselis, Michael A., Benkovic, Stephen J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC553339/
https://ncbi.nlm.nih.gov/pubmed/15738414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500713102
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