Assembly of the bacteriophage T4 primosome: Single-molecule and ensemble studies

Within replisomes for DNA replication, the primosome is responsible for unwinding double-stranded DNA and synthesizing RNA primers. Assembly of the bacteriophage T4 primosome on individual molecules of ssDNA or forked DNA (fDNA) has been studied by using FRET microscopy. On either DNA substrate, an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Zhiquan, Spiering, Michelle M., Trakselis, Michael A., Ishmael, Faoud T., Xi, Jun, Benkovic, Stephen J., Hammes, Gordon G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552937/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15728347/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0500327102
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