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Assembly of the bacteriophage T4 primosome: Single-molecule and ensemble studies

Within replisomes for DNA replication, the primosome is responsible for unwinding double-stranded DNA and synthesizing RNA primers. Assembly of the bacteriophage T4 primosome on individual molecules of ssDNA or forked DNA (fDNA) has been studied by using FRET microscopy. On either DNA substrate, an...

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Autors principals: Zhang, Zhiquan, Spiering, Michelle M., Trakselis, Michael A., Ishmael, Faoud T., Xi, Jun, Benkovic, Stephen J., Hammes, Gordon G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC552937/
https://ncbi.nlm.nih.gov/pubmed/15728347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500327102
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