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Architecture of the bacteriophage T4 primosome: Electron microscopy studies of helicase (gp41) and primase (gp61)

Replication of DNA requires helicase and primase activities as part of a primosome assembly. In bacteriophage T4, helicase and primase are separate polypeptides for which little structural information is available and whose mechanism of association within the primosome is not yet understood. Three-d...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Norcum, Mona T., Warrington, J. Anthony, Spiering, Michelle M., Ishmael, Faoud T., Trakselis, Michael A., Benkovic, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553339/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15738414/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0500713102
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