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DNA Unwinding by Ring-Shaped T4 Helicase gp41 Is Hindered by Tension on the Occluded Strand

The replicative helicase for bacteriophage T4 is gp41, which is a ring-shaped hexameric motor protein that achieves unwinding of dsDNA by translocating along one strand of ssDNA while forcing the opposite strand to the outside of the ring. While much study has been dedicated to the mechanism of bind...

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Detalhes bibliográficos
Main Authors: Ribeck, Noah, Saleh, Omar A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826741/
https://ncbi.nlm.nih.gov/pubmed/24250825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079237
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