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Single Molecule Studies Reveal Dynamics of DNA Unwinding by the Ring-Shaped T7 Helicase
Helicases are molecular motors that separate DNA strands for efficient replication of genomes. We probed the kinetics of individual ring-shaped T7 helicase molecules as they unwound double-stranded DNA (dsDNA) or translocated on single-stranded DNA (ssDNA). A distinctive DNA sequence dependence was...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699903/ https://ncbi.nlm.nih.gov/pubmed/17604719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.04.038 |
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