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Role of DNA polymerase κ in the maintenance of genomic stability

To ensure high cell viability and genomic stability, cells have evolved two major mechanisms to deal with the constant challenge of DNA replication fork arrest during S phase of the cell cycle: (1) induction of the ataxia telangiectasia and Rad3-related (ATR) replication checkpoint mechanism, and (2...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Oncol
Autori principali: Pillaire, Marie-Jeanne, Bétous, Rémy, Hoffmann, Jean-Sébastien
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905163/
https://ncbi.nlm.nih.gov/pubmed/27308312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mco.29902
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