Glatiramer Acetate and Nanny Proteins Restrict Access of the Multiple Sclerosis Autoantigen Myelin Basic Protein to the 26S Proteasome

Por Kuzina, Ekaterina, Kudriaeva, Anna, Smirnov, Ivan, Dubina, Michael V., Gabibov, Alexander, Belogurov, Alexey
Publicado em 2014

Administration of Myelin Basic Protein Peptides Encapsulated in Mannosylated Liposomes Normalizes Level of Serum TNF-α and IL-2 and Chemoattractants CCL2 and CCL4 in Multiple Scler...

Por Lomakin, Yakov, Belogurov, Alexey, Glagoleva, Irina, Stepanov, Alexey, Zakharov, Konstantin, Okunola, John, Smirnov, Ivan, Genkin, Dmitry, Gabibov, Alexander
Publicado no Mediators Inflamm (2016)

Multiple Sclerosis Autoantigen Myelin Basic Protein Escapes Control by Ubiquitination during Proteasomal Degradation

Por Belogurov, Alexey, Kudriaeva, Anna, Kuzina, Ekaterina, Smirnov, Ivan, Bobik, Tatyana, Ponomarenko, Natalia, Kravtsova-Ivantsiv, Yelena, Ciechanover, Aaron, Gabibov, Alexander
Publicado em 2014

Dissociation of the subunits of the calcium-independent receptor of α-latrotoxin as a result of two-step proteolysis

Por Krasnoperov, Valery, Deyev, Igor E., Serova, Oxana V., Xu, Chongfeng, Lu, Yun, Buryanovsky, Leonid, Gabibov, Alexander G., Neubert, Thomas A., Petrenko, Alexander G.
Publicado em 2009

CD206-Targeted Liposomal Myelin Basic Protein Peptides in Patients with Multiple Sclerosis Resistant to First-Line Disease-Modifying Therapies: A First-in-Human, Proof-of-Concept D...

Por Belogurov, Alexey, Zakharov, Konstantin, Lomakin, Yakov, Surkov, Kirill, Avtushenko, Sergey, Kruglyakov, Peter, Smirnov, Ivan, Makshakov, Gleb, Lockshin, Curtis, Gregoriadis, Gregory, Genkin, Dmitry, Gabibov, Alexander, Evdoshenko, Evgeniy
Publicado no Neurotherapeutics (2016)

Enzyme mimicry by the antiidiotypic antibody approach

Por Kolesnikov, Alexander V., Kozyr, Arina V., Alexandrova, Elena S., Koralewski, Frédéric, Demin, Alexander V., Titov, Mikhail I., Avalle, Bérangère, Tramontano, Alfonso, Paul, Sudhir, Thomas, Daniel, Gabibov, Alexander G., Friboulet, Alain
Publicado em 2000

Substrate Recognition of Anthrax Lethal Factor Examined by Combinatorial and Pre-steady-state Kinetic Approaches

Por Zakharova, Maria Yu., Kuznetsov, Nikita A., Dubiley, Svetlana A., Kozyr, Arina V., Fedorova, Olga S., Chudakov, Dmitry M., Knorre, Dmitry G., Shemyakin, Igor G., Gabibov, Alexander G., Kolesnikov, Alexander V.
Publicado em 2009

Exposure to the Epstein–Barr Viral Antigen Latent Membrane Protein 1 Induces Myelin-Reactive Antibodies In Vivo

Por Lomakin, Yakov, Arapidi, Georgii Pavlovich, Chernov, Alexander, Ziganshin, Rustam, Tcyganov, Evgenii, Lyadova, Irina, Butenko, Ivan Olegovich, Osetrova, Maria, Ponomarenko, Natalia, Telegin, Georgy, Govorun, Vadim Markovich, Gabibov, Alexander, Belogurov, Alexey
Publicado no Front Immunol (2017)

Tag7 (PGLYRP1) in Complex with Hsp70 Induces Alternative Cytotoxic Processes in Tumor Cells via TNFR1 Receptor

Por Yashin, Denis V., Ivanova, Olga K., Soshnikova, Natalia V., Sheludchenkov, Anton A., Romanova, Elena A., Dukhanina, Elena A., Tonevitsky, Alexander G., Gnuchev, Nikolai V., Gabibov, Alexander G., Georgiev, Georgii P., Sashchenko, Lidia P.
Publicado no J Biol Chem (2015)

Routes to covalent catalysis by reactive selection for nascent protein nucleophiles

Por Reshetnyak, Andrey V., Armentano, Maria Francesca, Ponomarenko, Natalia A., Vizzuso, Domenica, Durova, Oxana M., Ziganshin, Rustam, Serebryakova, Marina, Govorun, Vadim, Gololobov, Gennady, Morse III, Herbert C., Friboulet, Alain, Makker, Sudesh P., Gabibov, Alexander G., Tramontano, Alfonso
Publicado em 2007

Ubiquitin-independent proteosomal degradation of myelin basic protein contributes to development of neurodegenerative autoimmunity

Por Belogurov, Alexey, Kuzina, Ekaterina, Kudriaeva, Anna, Kononikhin, Alexey, Kovalchuk, Sergey, Surina, Yelena, Smirnov, Ivan, Lomakin, Yakov, Bacheva, Anna, Stepanov, Alexey, Karpova, Yaroslava, Lyupina, Yulia, Kharybin, Oleg, Melamed, Dobroslav, Ponomarenko, Natalia, Sharova, Natalia, Nikolaev, Eugene, Gabibov, Alexander
Publicado no FASEB J (2015)

Robotic QM/MM-driven maturation of antibody combining sites

Por Smirnov, Ivan V., Golovin, Andrey V., Chatziefthimiou, Spyros D., Stepanova, Anastasiya V., Peng, Yingjie, Zolotareva, Olga I., Belogurov, Alexey A., Kurkova, Inna N., Ponomarenko, Natalie A., Wilmanns, Matthias, Blackburn, G. Michael, Gabibov, Alexander G., Lerner, Richard A.
Publicado no Sci Adv (2016)

Reactibodies generated by kinetic selection couple chemical reactivity with favorable protein dynamics

Por Smirnov, Ivan, Carletti, Eugénie, Kurkova, Inna, Nachon, Florian, Nicolet, Yvain, Mitkevich, Vladimir A., Débat, Hélène, Avalle, Bérangère, Belogurov, Alexey A., Kuznetsov, Nikita, Reshetnyak, Andrey, Masson, Patrick, Tonevitsky, Alexander G., Ponomarenko, Natalia, Makarov, Alexander A., Friboulet, Alain, Tramontano, Alfonso, Gabibov, Alexander
Publicado em 2011

Divergent Immunomodulation Capacity of Individual Myelin Peptides—Components of Liposomal Therapeutic against Multiple Sclerosis

Por Ivanova, Vilena V., Khaiboullina, Svetlana F., Gomzikova, Marina O., Martynova, Ekaterina V., Ferreira, André M., Garanina, Ekaterina E., Sakhapov, Damir I., Lomakin, Yakov A., Khaibullin, Timur I., Granatov, Evgenii V., Khabirov, Farit A., Rizvanov, Albert A., Gabibov, Alexander, Belogurov, Alexey
Publicado no Front Immunol (2017)

Design of Targeted B Cell Killing Agents

Por Stepanov, Alexey V., Belogurov, Alexey A., Ponomarenko, Natalia A., Stremovskiy, Oleg A., Kozlov, Leonid V., Bichucher, Anna M., Dmitriev, Sergey E., Smirnov, Ivan V., Shamborant, Olga G., Balabashin, Dmitry S., Sashchenko, Lidia P., Tonevitsky, Alexander G., Friboulet, Alain, Gabibov, Alexander G., Deyev, Sergey M.
Publicado em 2011

Liposome-encapsulated peptides protect against experimental allergic encephalitis

Por Belogurov, Alexey A., Stepanov, Alexey V., Smirnov, Ivan V., Melamed, Dobroslav, Bacon, Andrew, Mamedov, Azad E., Boitsov, Vitali M., Sashchenko, Lidia P., Ponomarenko, Natalia A., Sharanova, Svetlana N., Boyko, Alexey N., Dubina, Michael V., Friboulet, Alain, Genkin, Dmitry D., Gabibov, Alexander G.
Publicado em 2013

Role of κ→λ light-chain constant-domain switch in the structure and functionality of A17 reactibody

Por Ponomarenko, Natalia, Chatziefthimiou, Spyros D., Kurkova, Inna, Mokrushina, Yuliana, Mokrushina, Yuliana, Stepanova, Anastasiya, Smirnov, Ivan, Avakyan, Marat, Bobik, Tatyana, Mamedov, Azad, Mitkevich, Vladimir, Belogurov, Alexey, Fedorova, Olga S., Dubina, Michael, Golovin, Andrey, Lamzin, Victor, Friboulet, Alain, Makarov, Alexander A., Wilmanns, Matthias, Gabibov, Alexander
Publicado em 2014

The Pathogenesis of the Demyelinating Form of Guillain-Barre Syndrome (GBS): Proteo-peptidomic and Immunological Profiling of Physiological Fluids

Por Ziganshin, Rustam H., Ivanova, Olga M., Lomakin, Yakov A., Belogurov, Alexey A., Kovalchuk, Sergey I., Azarkin, Igor V., Arapidi, Georgij P., Anikanov, Nikolay A., Shender, Victoria O., Piradov, Mikhail A., Suponeva, Natalia A., Vorobyeva, Anna A., Gabibov, Alexander G., Ivanov, Vadim T., Govorun, Vadim M.
Publicado no Mol Cell Proteomics (2016)

Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo

Por Ilyushin, Denis G., Smirnov, Ivan V., Belogurov, Alexey A., Dyachenko, Igor A., Zharmukhamedova, Tatiana Iu., Novozhilova, Tatjana I., Bychikhin, Eugene A., Serebryakova, Marina V., Kharybin, Oleg N., Murashev, Arkadii N., Anikienko, Konstantin A., Nikolaev, Eugene N., Ponomarenko, Natalia A., Genkin, Dmitry D., Blackburn, G. Michael, Masson, Patrick, Gabibov, Alexander G.
Publicado em 2013

Autoantibodies to myelin basic protein catalyze site-specific degradation of their antigen

Por Ponomarenko, Natalia A., Durova, Oxana M., Vorobiev, Ivan I., Belogurov, Alexey A., Kurkova, Inna N., Petrenko, Alexander G., Telegin, Georgy B., Suchkov, Sergey V., Kiselev, Sergey L., Lagarkova, Maria A., Govorun, Vadim M., Serebryakova, Marina V., Avalle, Bérangère, Tornatore, Pete, Karavanov, Alexander, Morse, Herbert C., Thomas, Daniel, Friboulet, Alain, Gabibov, Alexander G.
Publicado em 2006