Ubiquitin-independent proteosomal degradation of myelin basic protein contributes to development of neurodegenerative autoimmunity

Recent findings indicate that the ubiquitin–proteasome system is involved in the pathogenesis of cancer as well as autoimmune and several neurodegenerative diseases, and is thus a target for novel therapeutics. One disease that is related to aberrant protein degradation is multiple sclerosis, an aut...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Belogurov, Alexey, Kuzina, Ekaterina, Kudriaeva, Anna, Kononikhin, Alexey, Kovalchuk, Sergey, Surina, Yelena, Smirnov, Ivan, Lomakin, Yakov, Bacheva, Anna, Stepanov, Alexey, Karpova, Yaroslava, Lyupina, Yulia, Kharybin, Oleg, Melamed, Dobroslav, Ponomarenko, Natalia, Sharova, Natalia, Nikolaev, Eugene, Gabibov, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415016/
https://ncbi.nlm.nih.gov/pubmed/25634956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-259333
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