Administration of Myelin Basic Protein Peptides Encapsulated in Mannosylated Liposomes Normalizes Level of Serum TNF-α and IL-2 and Chemoattractants CCL2 and CCL4 in Multiple Sclerosis Patients

We have previously shown that immunodominant MBP peptides encapsulated in mannosylated liposomes (Xemys) effectively suppressed experimental allergic encephalomyelitis (EAE). Within the frames of the successfully completed phase I clinical trial, we investigated changes in the serum cytokine profile...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Lomakin, Yakov, Belogurov, Alexey, Glagoleva, Irina, Stepanov, Alexey, Zakharov, Konstantin, Okunola, John, Smirnov, Ivan, Genkin, Dmitry, Gabibov, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864531/
https://ncbi.nlm.nih.gov/pubmed/27239100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2847232
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